Dorsal horn neurons release extracellular ATP in a VNUT-dependent manner that underlies neuropathic pain

Dorsal horn neurons release extracellular ATP in a VNUT-dependent manner that underlies neuropathic pain

Purinergic receptor activation by extracellular ATP in the dorsal horn contributes to neuropathic pain, but which cell types release ATP in this context is not known. The authors show in a mouse model of neuropathic pain that ATP is released by dorsal horn neurons, a process requiring the vesicular...

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Bibliographic Details
Main Authors: Takahiro Masuda, Yui Ozono, Satsuki Mikuriya, Yuta Kohro, Hidetoshi Tozaki-Saitoh, Ken Iwatsuki, Hisayuki Uneyama, Reiko Ichikawa, Michael W. Salter, Makoto Tsuda, Kazuhide Inoue
Format: Article
Language:English
Published: Nature Publishing Group 2016-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12529

Internet

https://doi.org/10.1038/ncomms12529

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