The Janus Face of IL-33 Signaling in Tumor Development and Immune Escape

Interleukin-33 (IL-33), a member of the IL-1 cytokine family, plays a critical role in maintaining tissue homeostasis as well as pathological conditions, such as allergy, infectious disease, and cancer, by promoting type 1 and 2 immune responses. Through its specific receptor ST2, IL-33 exerts multi...

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Bibliographic Details
Main Authors: Mi-Ran Choi, Jeffrey A. Sosman, Bin Zhang
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
ST2
Online Access:https://www.mdpi.com/2072-6694/13/13/3281