Characteristics of allelic gene expression in human brain cells from single-cell RNA-seq data analysis

Abstract Background Monoallelic expression of autosomal genes has been implicated in human psychiatric disorders. However, there is a paucity of allelic expression studies in human brain cells at the single cell and genome wide levels. Results In this report, we reanalyzed a previously published sin...

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Bibliographic Details
Main Authors: Dejian Zhao, Mingyan Lin, Erika Pedrosa, Herbert M. Lachman, Deyou Zheng
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-017-4261-x