Detection of Low-Level Fosfomycin-Resistant Variants by Decreasing Glucose-6-Phosphate Concentration in Fosfomycin Susceptibility Determination

Detection of Low-Level Fosfomycin-Resistant Variants by Decreasing Glucose-6-Phosphate Concentration in Fosfomycin Susceptibility Determination

Mutations that confer low-level fosfomycin resistance (LLFR) but not clinical resistance in <i>Escherichia coli</i> are increasingly reported. LLFR strains can become clinically resistant under urinary tract physiological conditions or may act as gateways for highly resistant subpopulati...

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Bibliographic Details
Main Authors: Guillermo Martín-Gutiérrez, Fernando Docobo-Pérez, Jose Manuel Rodríguez-Martínez, Alvaro Pascual, Jesús Blázquez, Jeronimo Rodriguez-Beltrán
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Antibiotics
Subjects:
glucose-6-phosphate
fosfomycin resistance
<i>Escherichia coli</i>
MIC
urinary tract infection
Online Access:https://www.mdpi.com/2079-6382/9/11/802

Internet

https://www.mdpi.com/2079-6382/9/11/802

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