Elevated serum levels of interferon-regulated chemokines are biomarkers for active human systemic lupus erythematosus.
Systemic lupus erythematosus (SLE) is a serious systemic autoimmune disorder that affects multiple organ systems and is characterized by unpredictable flares of disease. Recent evidence indicates a role for type I interferon (IFN) in SLE pathogenesis; however, the downstream effects of IFN pathway a...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2006-12-01
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Series: | PLoS Medicine |
Online Access: | http://europepmc.org/articles/PMC1702557?pdf=render |