Elevated serum levels of interferon-regulated chemokines are biomarkers for active human systemic lupus erythematosus.

Systemic lupus erythematosus (SLE) is a serious systemic autoimmune disorder that affects multiple organ systems and is characterized by unpredictable flares of disease. Recent evidence indicates a role for type I interferon (IFN) in SLE pathogenesis; however, the downstream effects of IFN pathway a...

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Bibliographic Details
Main Authors: Jason W Bauer, Emily C Baechler, Michelle Petri, Franak M Batliwalla, Dianna Crawford, Ward A Ortmann, Karl J Espe, Wentian Li, Dhavalkumar D Patel, Peter K Gregersen, Timothy W Behrens
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-12-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC1702557?pdf=render