Vaccinia Virus Shuffling: deVV5, a Novel Chimeric Poxvirus with Improved Oncolytic Potency

Vaccinia Virus Shuffling: deVV5, a Novel Chimeric Poxvirus with Improved Oncolytic Potency

Oncolytic virus (OV) therapy has emerged as a promising approach for cancer treatment with the potential to be less toxic and more efficient than classic cancer therapies. Various types of OVs in clinical development, including Vaccinia virus (VACV)-derived OVs, have shown good safety profiles, but...

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Bibliographic Details
Main Authors: Marine Ricordel, Johann Foloppe, Delphine Antoine, Annie Findeli, Juliette Kempf, Pascale Cordier, Aude Gerbaud, Benoit Grellier, Monika Lusky, Eric Quemeneur, Philippe Erbs
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Cancers
Subjects:
vaccinia virus
directed evolution
genome shuffling
deVV5-fcu1
Online Access:http://www.mdpi.com/2072-6694/10/7/231

Internet

http://www.mdpi.com/2072-6694/10/7/231

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