Genetic deletion of soluble epoxide hydrolase delays the progression of Alzheimer’s disease

Abstract Background Soluble epoxide hydrolase (sEH) is a bifunctional enzyme with COOH-terminal hydrolase and NH2-terminal lipid phosphatase activities. It is expressed in various cell types in the brain and is involved in the pathogenesis of inflammatory and neurodegenerative diseases. Alzheimer’s...

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Bibliographic Details
Main Authors: Hsueh-Te Lee, Kuan-I Lee, Chia-Hui Chen, Tzong-Shyuan Lee
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:https://doi.org/10.1186/s12974-019-1635-9