The role of the tumor stroma in ovarian cancer

The tumor microenvironment, consisting of stromal myofibroblasts, endothelial cells and leukocytes, is growingly perceived to be a major contributor to the pathogenesis and disease progression in practically all cancer types. Stromal myofibroblasts produce angiogenic factors, proteases, growth facto...

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Bibliographic Details
Main Authors: Ben eDavidson, Claes eTrope, Reuven eReich
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00104/full