Inhibition of Germinal Centre Apoptotic Programmes by Epstein-Barr Virus

To establish a persistent latent infection, Epstein-Barr virus (EBV) faces a challenge in that the virus-infected host cell must transit through the germinal centre reaction. This is a site of B cell differentiation where antibody responses are optimised, and the selection criteria for B cells are s...

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Bibliographic Details
Main Authors: Lindsay C. Spender, Gareth J. Inman
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Advances in Hematology
Online Access:http://dx.doi.org/10.1155/2011/829525