"Salvage microbiology": detection of bacteria directly from clinical specimens following initiation of antimicrobial treatment.

PCR coupled with electrospray ionization mass spectrometry (ESI-MS) is a diagnostic approach that has demonstrated the capacity to detect pathogenic organisms from culture negative clinical samples after antibiotic treatment has been initiated. [1] We describe the application of PCR/ESI-MS for detec...

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Bibliographic Details
Main Authors: John J Farrell, Rangarajan Sampath, David J Ecker, Robert A Bonomo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3692526?pdf=render