Stem-loop structure preference for site-specific RNA editing by APOBEC3A and APOBEC3G
APOBEC3A and APOBEC3G cytidine deaminases inhibit viruses and endogenous retrotransposons. We recently demonstrated the novel cellular C-to-U RNA editing function of APOBEC3A and APOBEC3G. Both enzymes deaminate single-stranded DNAs at multiple TC or CC nucleotide sequences, but edit only a select s...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2017-12-01
|
Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/4136.pdf |