MK3 modulation affects BMI1-dependent and independent cell cycle check-points.

MK3 modulation affects BMI1-dependent and independent cell cycle check-points.

Although the MK3 gene was originally found deleted in some cancers, it is highly expressed in others. The relevance of MK3 for oncogenesis is currently not clear. We recently reported that MK3 controls ERK activity via a negative feedback mechanism. This prompted us to investigate a potential role f...

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Bibliographic Details
Main Authors: Peggy Prickaerts, Hanneke E C Niessen, Vivian E H Dahlmans, Frank Spaapen, Juliette Salvaing, Jolien Vanhove, Claudia Geijselaers, Stefanie J J Bartels, Iris Partouns, Dietbert Neumann, Ernst-Jan Speel, Yoshihiro Takihara, Bradly G Wouters, Jan Willem Voncken
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4390245?pdf=render

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http://europepmc.org/articles/PMC4390245?pdf=render

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