Histamine (H1) Receptors, Cyclooxygenase Pathway and Nitric Oxide Formation Involved in Rat Tracheal Smooth Muscle Relaxant Effect of Berberine

In this study we aimed to examine the relaxant effect of berberine, a compound extracted from a variety of herbs, on rat tracheal smooth muscle (TSM) and its possible mechanism(s). Cumulative concentrations of berberine (20, 65, 200 and 600 μg/mL) were added on pre-contracted TSM by methacholine or...

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Bibliographic Details
Main Authors: Saeideh Saadat, Farzaneh Naghdi, Vahideh Ghorani, Hassan Rakhshandeh, Mohammad Hosein Boskabady
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2019-06-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/2182