Diminished macrophage apoptosis and reactive oxygen species generation after phorbol ester stimulation in Crohn's disease.

Diminished macrophage apoptosis and reactive oxygen species generation after phorbol ester stimulation in Crohn's disease.

BACKGROUND:Crohn's Disease (CD) is a chronic relapsing disorder characterized by granulomatous inflammation of the gastrointestinal tract. Although its pathogenesis is complex, we have recently shown that CD patients have a systemic defect in macrophage function, which results in the defective...

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Bibliographic Details
Main Authors: Christine D Palmer, Farooq Z Rahman, Gavin W Sewell, Afshan Ahmed, Margaret Ashcroft, Stuart L Bloom, Anthony W Segal, Andrew M Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2771353?pdf=render

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http://europepmc.org/articles/PMC2771353?pdf=render

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