Redox-Responsive Heparin–Chlorambucil Conjugate Polymeric Prodrug for Improved Anti-Tumor Activity

Polymeric prodrug-based delivery systems have been extensively studied to find a better solution for the limitations of a single drug and to improve the therapeutic and pharmacodynamics properties of chemotherapeutic agents, which can lead to efficient therapy. In this study, redox-responsive disulf...

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Bibliographic Details
Main Authors: Abegaz Tizazu Andrgie, Yihenew Simegniew Birhan, Tefera Worku Mekonnen, Endiries Yibru Hanurry, Haile Fentahun Darge, Rong-Ho Lee, Hsiao-Ying Chou, Hsieh-Chih Tsai
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/12/1/43