Human Prostate Cancer is Characterized by an Increase in Urea Cycle Metabolites

Human Prostate Cancer is Characterized by an Increase in Urea Cycle Metabolites

Despite it being the most common incident of cancer among men, the pathophysiological mechanisms contributing to prostate cancer (PCa) are still poorly understood. Altered mitochondrial metabolism is postulated to play a role in the development of PCa. To determine the key metabolites (which include...

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Bibliographic Details
Main Authors: Yaping Shao, Andras Franko, Martin Heni, Jörg Hennenlotter, Miriam Hoene, Chunxiu Hu, Xinyu Liu, Xinjie Zhao, Qingqing Wang, Andreas L. Birkenfeld, Tilman Todenhöfer, Arnulf Stenzl, Andreas Peter, Hans-Ulrich Häring, Rainer Lehmann, Guowang Xu, Stefan Z. Lutz
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
prostate cancer
metabolomics
urea cycle
fumarate
oncometabolite
NFκB
Online Access:https://www.mdpi.com/2072-6694/12/7/1814

Internet

https://www.mdpi.com/2072-6694/12/7/1814

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