Effects of sedatives and opioids on trigger and cycling asynchronies throughout mechanical ventilation: an observational study in a large dataset from critically ill patients

Effects of sedatives and opioids on trigger and cycling asynchronies throughout mechanical ventilation: an observational study in a large dataset from critically ill patients

Abstract Background In critically ill patients, poor patient-ventilator interaction may worsen outcomes. Although sedatives are often administered to improve comfort and facilitate ventilation, they can be deleterious. Whether opioids improve asynchronies with fewer negative effects is unknown. We h...

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Main Authors: Candelaria de Haro, Rudys Magrans, Josefina López-Aguilar, Jaume Montanyà, Enrico Lena, Carles Subirà, Sol Fernandez-Gonzalo, Gemma Gomà, Rafael Fernández, Guillermo M. Albaiceta, Yoanna Skrobik, Umberto Lucangelo, Gastón Murias, Ana Ochagavia, Robert M. Kacmarek, Montserrat Rue, Lluís Blanch, for the Asynchronies in the Intensive Care Unit (ASYNICU) Group
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Critical Care
Subjects:
Asynchronies
Mechanical ventilation
Sedatives
Opioids
Double cycling
Ineffective inspiratory efforts during expiration
Online Access:http://link.springer.com/article/10.1186/s13054-019-2531-5

Internet

http://link.springer.com/article/10.1186/s13054-019-2531-5

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