KRAS genotypic changes of circulating tumor cells during treatment of patients with metastatic colorectal cancer.

Circulating tumor cells (CTCs) could represent a non-invasive source of cancer cells used for longitudinal monitoring of the tumoral mutation status throughout the course of the disease. The aims of the present study were to investigate the detection of KRAS mutations in CTCs from patients with meta...

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Bibliographic Details
Main Authors: Aristea Kalikaki, Helen Politaki, John Souglakos, Stella Apostolaki, Elisavet Papadimitraki, Nefeli Georgoulia, Maria Tzardi, Dimitris Mavroudis, Vassilis Georgoulias, Alexandra Voutsina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4138105?pdf=render