Treatment of ErbB2 breast cancer by mitochondrial targeting

Abstract Background ErbB2 breast cancer still remains an unmet need due to primary and/or acquired resistance to current treatment strategies. MEDICA compounds consist of synthetic long-chain α,ω-dicarboxylic acids previously reported to suppress breast cancer in PyMT transgenic mice. Methods MEDICA...

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Bibliographic Details
Main Authors: Sophia Eldad, Rachel Hertz, Gilad Vainer, Ann Saada, Jacob Bar-Tana
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Cancer & Metabolism
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40170-020-00223-8