A Therapeutic Approach to Nasopharyngeal Carcinomas by DNAzymes Targeting EBV LMP-1 Gene

Epstein-Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) has been known to have oncogenic properties during latent infection in nasopharyngeal carcinoma (NPC). Genetic manipulation of LMP1 expression may provide a novel strategy for the treatment of NPC. DNAzymes are synthetic, single-stran...

Full description

Bibliographic Details
Main Authors: Lun-Quan Sun, Ya Cao, Xiaoqian Ma, Zhongxin Lu, Lifang Yang
Format: Article
Language:English
Published: MDPI AG 2010-09-01
Series:Molecules
Subjects:
NPC
Online Access:http://www.mdpi.com/1420-3049/15/9/6127/