Enhanced Efficacy of Doxorubicin by microRNA-499-Mediated Improvement of Tumor Blood Flow

Enhanced Efficacy of Doxorubicin by microRNA-499-Mediated Improvement of Tumor Blood Flow

Genetic therapy using microRNA-499 (miR-499) was combined with chemotherapy for the advanced treatment of cancer. Our previous study showed that miR-499 suppressed tumor growth through the inhibition of vascular endothelial growth factor (VEGF) production and subsequent angiogenesis. In the present...

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Bibliographic Details
Main Authors: Ayaka Okamoto, Tomohiro Asai, Sho Ryu, Hidenori Ando, Noriyuki Maeda, Takehisa Dewa, Naoto Oku
Format: Article
Language:English
Published: MDPI AG 2016-01-01
Series:Journal of Clinical Medicine
Subjects:
microRNA
miR-499
cancer therapy
gene delivery
liposomes
tumor blood perfusion
Online Access:http://www.mdpi.com/2077-0383/5/1/10

Internet

http://www.mdpi.com/2077-0383/5/1/10

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