A transgenic zebrafish line for in vivo visualisation of neutrophil myeloperoxidase.

The neutrophil enzyme myeloperoxidase (MPO) is a major enzyme made by neutrophils to generate antimicrobial and immunomodulatory compounds, notably hypochlorous acid (HOCl), amplifying their capacity for destroying pathogens and regulating inflammation. Despite its roles in innate immunity, the impo...

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Bibliographic Details
Main Authors: Kyle D Buchan, Tomasz K Prajsnar, Nikolay V Ogryzko, Nienke W M de Jong, Michiel van Gent, Julia Kolata, Simon J Foster, Jos A G van Strijp, Stephen A Renshaw
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0215592