Effect of miR-132 on bupivacaine-induced neurotoxicity in human neuroblastoma cell line

Background: Local anesthetics (LAs) may generate neurotoxicity in neurons. In the current study, we explored the mechanisms by which microRNA-132 (miR-132) regulated the neurotoxicity of human neuroblastoma cells (SH-SY5Y) induced by bupivacaine (BUP). Methods: CCK-8, flow cytometry, EdU detection,...

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Bibliographic Details
Main Authors: Huiying Zhang, Jianzhong Lin, Tingting Hu, Zhiyun Ren, Weiwan Wang, Qiyue He
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319300210