Composite trait Mendelian randomization reveals distinct metabolic and lifestyle consequences of differences in body shape

Composite trait Mendelian randomization reveals distinct metabolic and lifestyle consequences of differences in body shape

Jonathan Sulc et al. use principal component analysis and Mendelian randomization to conduct a comprehensive analysis of 14 body morphology metrics using data from the UK Biobank. Their results suggest that body size and adiposity have distinct impacts on obesity-related outcomes and highlight a BMI...

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Bibliographic Details
Main Authors: Jonathan Sulc, Anthony Sonrel, Ninon Mounier, Chiara Auwerx, Eirini Marouli, Liza Darrous, Bogdan Draganski, Tuomas O. Kilpeläinen, Peter Joshi, Ruth J. F. Loos, Zoltán Kutalik
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02550-y

Internet

https://doi.org/10.1038/s42003-021-02550-y

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