A Novel Melt-Dispersion Technique for Simplistic Preparation of Chlorpromazine-Loaded Polycaprolactone Nanocapsules

A Novel Melt-Dispersion Technique for Simplistic Preparation of Chlorpromazine-Loaded Polycaprolactone Nanocapsules

The aim of this study was to design, synthesize and optimize chlorpromazine hydrochloride (CPZ)-loaded, poly-ε-caprolactone (PCL) based nanocapsules, intended for site specific delivery to the frontal lobe, using a novel melt-dispersion technique that is non-arduous, inexpensive and devoid of any h...

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Bibliographic Details
Main Authors: Thiresen Govender, Yahya E. Choonara, Pradeep Kumar, Lisa C. Du Toit, Girish Modi, Dinesh Naidoo, Viness Pillay
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Polymers
Subjects:
neurotherapy
chlorpromazine hydrochloride
poly-ε-caprolactone
Polysorbate 80
melt-dispersion technique
nanocapsules
central composite design
Online Access:http://www.mdpi.com/2073-4360/7/6/1145

Internet

http://www.mdpi.com/2073-4360/7/6/1145

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