An iteration model for identifying essential proteins by combining comprehensive PPI network with biological information

Abstract Background Essential proteins have great impacts on cell survival and development, and played important roles in disease analysis and new drug design. However, since it is inefficient and costly to identify essential proteins by using biological experiments, then there is an urgent need for...

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Bibliographic Details
Main Authors: Shiyuan Li, Zhen Zhang, Xueyong Li, Yihong Tan, Lei Wang, Zhiping Chen
Format: Article
Language:English
Published: BMC 2021-09-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-021-04300-7