Exacerbation of Allergic Airway Inflammation in Mice Lacking ECTO-5′-Nucleotidase (CD73)

Exacerbation of Allergic Airway Inflammation in Mice Lacking ECTO-5′-Nucleotidase (CD73)

The airways are a target tissue of type I allergies and atopy is the main etiological factor of bronchial asthma. A predisposition to allergy and individual response to allergens are dependent upon environmental and host factors. Early studies performed to clarify the role of extracellular adenosine...

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Bibliographic Details
Main Authors: Elisabetta Caiazzo, Ida Cerqua, Maria Antonietta Riemma, Roberta Turiello, Armando Ialenti, Jurgen Schrader, Giuseppe Fiume, Carmen Caiazza, Fiorentina Roviezzo, Silvana Morello, Carla Cicala
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Pharmacology
Subjects:
CD73
ecto-5′-nucleotidase
adenosine
sensitization
airways
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.589343/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.589343/full

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