Contrasted TCRβ diversity of CD8+ and CD8- T cells in rainbow trout.

Teleost fish express highly diverse naive TCRβ (TRB) repertoires and mount strong public and private clonal responses upon infection with pathogens. Fish T cells express typical markers such as CD8, CD4-1 and CD4-2, CD3, CD28 and CTLA4. Fish CD8(+) T cells have been shown to be responsible for antig...

Full description

Bibliographic Details
Main Authors: Rosario Castro, Fumio Takizawa, Wahiba Chaara, Aurélie Lunazzi, Thi Huong Dang, Bernd Koellner, Edwige Quillet, Adrien Six, Uwe Fischer, Pierre Boudinot
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23565199/?tool=EBI