Astaxanthin and Docosahexaenoic Acid Reverse the Toxicity of the Maxi-K (BK) Channel Antagonist Mycotoxin Penitrem A

Astaxanthin and Docosahexaenoic Acid Reverse the Toxicity of the Maxi-K (BK) Channel Antagonist Mycotoxin Penitrem A

Penitrem A (PA) is a food mycotoxin produced by several terrestrial and few marine Penicillium species. PA is a potent tremorgen through selective antagonism of the calcium-dependent potassium BK (Maxi-K) channels. Discovery of natural products that can prevent the toxic effects of PA is important f...

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Bibliographic Details
Main Authors: Amira A. Goda, Khayria M. Naguib, Magdy M. Mohamed, Hassan A. Amra, Somaia A. Nada, Abdel-Rahman B. Abdel-Ghaffar, Chris R. Gissendanner, Khalid A. El Sayed
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Marine Drugs
Subjects:
astaxanthin
BK (Maxi-K) channels
docosahexaenoic acid
food mycotoxin
penitrem A
toxicity
Online Access:http://www.mdpi.com/1660-3397/14/11/208

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http://www.mdpi.com/1660-3397/14/11/208

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