HIV-1 Coreceptor Usage Assessment by Ultra-Deep Pyrosequencing and Response to Maraviroc.

HIV-1 Coreceptor Usage Assessment by Ultra-Deep Pyrosequencing and Response to Maraviroc.

Maraviroc is an HIV entry inhibitor that alters the conformation of CCR5 and is poorly efficient in patients infected by viruses that use CXCR4 as an entry coreceptor. The goal of this study was to assess the capacity of ultra-deep pyrosequencing (UDPS) and different data analysis approaches to char...

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Bibliographic Details
Main Authors: Christophe Rodriguez, Cathia Soulié, Anne-Geneviève Marcelin, Vincent Calvez, Diane Descamps, Charlotte Charpentier, Philippe Flandre, Patricia Recordon-Pinson, Pantxika Bellecave, Jean-Michel Pawlotsky, Bernard Masquelier, ANRS AC11 Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4466260?pdf=render

Internet

http://europepmc.org/articles/PMC4466260?pdf=render

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