The Potential Effects of Oxidative Stress-Related Plasma Abnormal Protein Aggregate Levels on Brain Volume and Its Neuropsychiatric Consequences in Parkinson’s Disease

Background. Oxidative stress has been implicated in the pathogenesis of many diseases, including Parkinson’s disease. Large protein aggregates may be produced after the breakdown of the proteostasis network due to overt oxidative stress. Meanwhile, brain volume loss and neuropsychiatric deficits are...

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Bibliographic Details
Main Authors: Pei-Chin Chen, Chiun-Chieh Yu, Yueh-Sheng Chen, Cheng-Hsien Lu, Shan-Ho Chan, Kun-Hsien Chou, Mei-Hsiu Chen, Meng-Hsiang Chen, Wei-Che Lin
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2021/3666327