Novel Indole-Based Hydrazones as Potent Inhibitors of the α-class Carbonic Anhydrase from Pathogenic Bacterium <i>Vibrio cholerae</i>

Novel Indole-Based Hydrazones as Potent Inhibitors of the α-class Carbonic Anhydrase from Pathogenic Bacterium <i>Vibrio cholerae</i>

Due to the increasing resistance of currently used antimicrobial drugs, there is an urgent problem for the treatment of cholera disease, selective inhibition of the α-class carbonic anhydrases (CA, EC 4.2.1.1) from the pathogenic bacterium <i>Vibrio cholerae</i> (VcCA) presents an altern...

Full description

Bibliographic Details
Main Authors: Kübra Demir-Yazıcı, Özlen Güzel-Akdemir, Andrea Angeli, Claudiu T. Supuran, Atilla Akdemir
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
carbonic anhydrase
indole
sulfonamides
hydrazones
<i>Vibrio cholerae</i>
enzyme inhibition
Online Access:https://www.mdpi.com/1422-0067/21/9/3131

Internet

https://www.mdpi.com/1422-0067/21/9/3131

Similar Items