Sex-Associated Differential mRNA Expression of Cytokines and Its Regulation by Sex Steroids in Different Brain Regions in a Plasmodium berghei ANKA Model of Cerebral Malaria

Cerebral malaria (CM) is the major complication associated with death in malaria patients, and its pathogenesis is associated with excessive proinflammatory cytokine production. Notably, the severity and mortality of natural infections with Plasmodium are higher in males than females, suggesting tha...

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Main Authors: Martha Legorreta-Herrera, Karen E. Nava-Castro, Margarita I. Palacios-Arreola, Rosalía Hernández-Cervantes, Jesús Aguilar-Castro, Luis A. Cervantes-Candelas, Jorge Morales-Montor
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2018/5258797