Major Peptides from Amaranth (Amaranthus cruentus) Protein Inhibit HMG-CoA Reductase Activity

Major Peptides from Amaranth (Amaranthus cruentus) Protein Inhibit HMG-CoA Reductase Activity

The objective of this study was to identify the major peptides generated by the in vitro hydrolysis of Amaranthus cruentus protein and to verify the effect of these peptides on the activity of 3-hydroxy-3-methyl-glutaryl-CoA reductase (HMG-CoA reductase), a key enzyme in cholesterol biosynthesis. A...

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Bibliographic Details
Main Authors: Rosana Aparecida Manólio Soares, Simone Mendonça, Luíla Ívini Andrade de Castro, Amanda Caroline Cardoso Corrêa Carlos Menezes, José Alfredo Gomes Arêas
Format: Article
Language:English
Published: MDPI AG 2015-02-01
Series:International Journal of Molecular Sciences
Subjects:
bioactive peptides
de novo sequencing
mass spectrometry
amaranth
HMG-CoA reductase activity
Online Access:http://www.mdpi.com/1422-0067/16/2/4150

Internet

http://www.mdpi.com/1422-0067/16/2/4150

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