The effect of orexin-A on cardiac dysfunction mediated by NADPH oxidase-derived superoxide anion in ventrolateral medulla.

Hypocretin/orexin-producing neurons, located in the perifornical region of the lateral hypothalamus area (LHA) and projecting to the brain sites of rostral ventrolateral medulla (RVLM), involve in the increase of sympathetic activity, thereby regulating cardiovascular function. The current study was...

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Bibliographic Details
Main Authors: Jun Chen, Chunmei Xia, Jin Wang, Meiyan Jiang, Huanhuan Zhang, Chengrong Zhang, Minxia Zhu, Linlin Shen, Danian Zhu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3724905?pdf=render