Transcriptome analysis of porcine PBMCs reveals lipopolysaccharide-induced immunomodulatory responses and crosstalk of immune and glucocorticoid receptor signaling

Transcriptome analysis of porcine PBMCs reveals lipopolysaccharide-induced immunomodulatory responses and crosstalk of immune and glucocorticoid receptor signaling

The current level of knowledge on transcriptome responses triggered by endotoxins and glucocorticoids in immune cells in pigs is limited. Therefore, in the present study, we treated porcine peripheral blood mononuclear cells (PBMCs) with lipopolysaccharide (LPS) and dexamethasone (DEX) separately or...

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Bibliographic Details
Main Authors: Zhiwei Li, Nares Trakooljul, Frieder Hadlich, Siriluck Ponsuksili, Klaus Wimmers, Eduard Murani
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Virulence
Subjects:
transcriptome
porcine pbmcs
lipopolysaccharide
immune signaling
dexamethasone
glucocorticoid receptor signaling
Online Access:http://dx.doi.org/10.1080/21505594.2021.1948276

Internet

http://dx.doi.org/10.1080/21505594.2021.1948276

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