Inhibition of microRNA-29a alleviates hyperoxia-induced bronchopulmonary dysplasia in neonatal mice via upregulation of GAB1

Inhibition of microRNA-29a alleviates hyperoxia-induced bronchopulmonary dysplasia in neonatal mice via upregulation of GAB1

Abstract Background The main features of bronchopulmonary dysplasia (BPD) are alveolar simplification, pulmonary growth arrest, and abnormal lung function. Multiple studies have highlighted microRNA-29 (miR-29) as a potential biomarker for lung diseases and cancers. Upregulation of miR-29a has been...

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Bibliographic Details
Main Authors: Yu Hu, Liang Xie, Jing Yu, Hongling Fu, Dan Zhou, Hanmin Liu
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Molecular Medicine
Subjects:
Bronchopulmonary dysplasia
MicroRNA-29a
GAB1
Apoptosis
Hyperoxia
MLE-12
Online Access:https://doi.org/10.1186/s10020-019-0127-9

Internet

https://doi.org/10.1186/s10020-019-0127-9

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