Role of Decorin Core Protein in Collagen Organisation in Congenital Stromal Corneal Dystrophy (CSCD).

The role of Decorin in organising the extracellular matrix was examined in normal human corneas and in corneas from patients with Congenital Stromal Corneal Dystrophy (CSCD). In CSCD, corneal clouding occurs due to a truncating mutation (c.967delT) in the decorin (DCN) gene. Normal human Decorin pro...

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Bibliographic Details
Main Authors: Christina S Kamma-Lorger, Christian Pinali, Juan Carlos Martínez, Jon Harris, Robert D Young, Cecilie Bredrup, Eva Crosas, Marc Malfois, Eyvind Rødahl, Keith M Meek, Carlo Knupp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4734740?pdf=render