Some Metabolites Act as Second Messengers in Yeast Chronological Aging

Some Metabolites Act as Second Messengers in Yeast Chronological Aging

The concentrations of some key metabolic intermediates play essential roles in regulating the longevity of the chronologically aging yeast Saccharomyces cerevisiae. These key metabolites are detected by certain ligand-specific protein sensors that respond to concentration changes of the key metaboli...

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Bibliographic Details
Main Authors: Karamat Mohammad, Paméla Dakik, Younes Medkour, Mélissa McAuley, Darya Mitrofanova, Vladimir I. Titorenko
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:International Journal of Molecular Sciences
Subjects:
yeast
chronological aging
mechanisms of longevity regulation
metabolism
cell signaling
second messengers
mitochondria
interorganellar communications
proteostasis
regulated cell death
Online Access:http://www.mdpi.com/1422-0067/19/3/860

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http://www.mdpi.com/1422-0067/19/3/860

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