The dose response of inhaled LPS challenge in healthy subjects

Lipopolysaccharide (LPS) inhalation causes neutrophilic airway inflammation. We used LPS produced to Good Manufacturing Practice (GMP) standards to characterise the dose response. A total of 15 healthy non-smoking subjects inhaled 5-, 15- and 50-µg LPS. Whole blood cell counts and serum C-reactive p...

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Bibliographic Details
Main Authors: Alex Mulvanny, Natalie Jackson, Caroline Pattwell, Sophie Wolosianka, Thomas Southworth, Dave Singh
Format: Article
Language:English
Published: SAGE Publishing 2018-06-01
Series:European Journal of Inflammation
Online Access:https://doi.org/10.1177/2058739218784820