Androgen receptor expression is required to ensure development of adult Leydig cells and to prevent development of steroidogenic cells with adrenal characteristics in the mouse testis

Androgen receptor expression is required to ensure development of adult Leydig cells and to prevent development of steroidogenic cells with adrenal characteristics in the mouse testis

Abstract Background The interstitium of the mouse testis contains Leydig cells and a small number of steroidogenic cells with adrenal characteristics which may be derived from the fetal adrenal during development or may be a normal subset of the developing fetal Leydig cells. Currently it is not kno...

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Bibliographic Details
Main Authors: Peter J. O’Shaughnessy, Rod T. Mitchell, Ana Monteiro, Laura O’Hara, Lyndsey Cruickshanks, Hedi Claahsen-van der Grinten, Pamela Brown, Margaret Abel, Lee B. Smith
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Developmental Biology
Subjects:
Testis
Androgen receptor
Leydig
Adrenal
Development
Stereology
Online Access:http://link.springer.com/article/10.1186/s12861-019-0189-5

Internet

http://link.springer.com/article/10.1186/s12861-019-0189-5

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