A map of protein dynamics during cell-cycle progression and cell-cycle exit.

The cell-cycle field has identified the core regulators that drive the cell cycle, but we do not have a clear map of the dynamics of these regulators during cell-cycle progression versus cell-cycle exit. Here we use single-cell time-lapse microscopy of Cyclin-Dependent Kinase 2 (CDK2) activity follo...

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Bibliographic Details
Main Authors: Sara Gookin, Mingwei Min, Harsha Phadke, Mingyu Chung, Justin Moser, Iain Miller, Dylan Carter, Sabrina L Spencer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-09-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC5608403?pdf=render