Formation of neutrophil extracellular traps under low oxygen level

Formation of neutrophil extracellular traps under low oxygen level

Since their discovery, neutrophil extracellular traps (NETs) have been characterized as a fundamental host innate immune defense mechanism. Conversely, excessive NET release may have a variety of detrimental consequences for the host. A fine balance between NET formation and elimination is necessary...

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Bibliographic Details
Main Authors: Katja Branitzki-Heinemann, Helene Möllerherm, Lena Völlger, Diab Hussein, Nicole de Buhr, Stefanie Blodkamp, Friederike Reuner, Graham Brogden, Hassan Y. Naim, Maren Von Köckritz-Blickwede
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Immunology
Subjects:
Cholesterol
Neutrophils
innate immunity
hypoxia
neutrophil extracellular traps
HIF-1α
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00518/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00518/full

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