How Do Telomere Abnormalities Regulate the Biology of Neuroblastoma?
Telomere maintenance plays important roles in genome stability and cell proliferation. Tumor cells acquire replicative immortality by activating a telomere-maintenance mechanism (TMM), either telomerase, a reverse transcriptase, or the alternative lengthening of telomeres (ALT) mechanism. Recent adv...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-07-01
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Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/11/8/1112 |