How Do Telomere Abnormalities Regulate the Biology of Neuroblastoma?

How Do Telomere Abnormalities Regulate the Biology of Neuroblastoma?

Telomere maintenance plays important roles in genome stability and cell proliferation. Tumor cells acquire replicative immortality by activating a telomere-maintenance mechanism (TMM), either telomerase, a reverse transcriptase, or the alternative lengthening of telomeres (ALT) mechanism. Recent adv...

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Bibliographic Details
Main Authors: Jesmin Akter, Takehiko Kamijo
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biomolecules
Subjects:
telomere maintenance
TERT
ATRX
telomerase
ALT
neuroblastoma
Online Access:https://www.mdpi.com/2218-273X/11/8/1112

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