Therapeutic strategies to remodel immunologically cold tumors

Abstract Immune checkpoint inhibitors (ICIs) induce a durable response in a wide range of tumor types, but only a minority of patients outside these ‘responsive’ tumor types respond, with some totally resistant. The primary predictor of intrinsic immune resistance to ICIs is the complete or near‐com...

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Bibliographic Details
Main Authors: Minyu Wang, Sen Wang, Jayesh Desai, Joseph A Trapani, Paul J Neeson
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Clinical & Translational Immunology
Subjects:
Online Access:https://doi.org/10.1002/cti2.1226