Standardization and experience may influence the survival of laparoscopic radical hysterectomy for cervical cancer

Objective: Minimally invasive radical hysterectomy has been shown to be associated with poorer outcome in an influential prospective, randomized trial. However, many centers worldwide performing minimally invasive radical hysterectomy have data and experience that prove otherwise. We aim to review s...

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Main Authors: Chyi-Long Lee, Kuan-Gen Huang, Peng Teng Chua, Marie Christine Valerie R. Mendoza, Pei San Lee, Siew Yen Lai
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Taiwanese Journal of Obstetrics & Gynecology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1028455921000644
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spelling doaj-2dec73e444dd44e9bac9ba2770c3037f2021-05-08T04:21:59ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592021-05-01603463467Standardization and experience may influence the survival of laparoscopic radical hysterectomy for cervical cancerChyi-Long Lee0Kuan-Gen Huang1Peng Teng Chua2Marie Christine Valerie R. Mendoza3Pei San Lee4Siew Yen Lai5Department of Obstetrics & Gynaecology, Division of Gynaecological Endoscopy & Minimally Invasive Therapy, Chang Gung Memorial Hospital, Chang Gung University, Linkou, TaiwanDepartment of Obstetrics & Gynaecology, Division of Gynaecological Endoscopy & Minimally Invasive Therapy, Chang Gung Memorial Hospital, Chang Gung University, Linkou, TaiwanDepartment of Obstetrics & Gynaecology, Division of Gynaecological Endoscopy & Minimally Invasive Therapy, Chang Gung Memorial Hospital, Chang Gung University, Linkou, Taiwan; Mahkota Medical Centre, Malacca, Malaysia; Corresponding author. Mahkota Medical Centre, Department of Obstetrics & Gynaecology, No.3, Mahkota Melaka, Jalan Merdeka, 75000, Melaka, Malaysia. Fax: +6 06 281 0560.Department of Obstetrics & Gynaecology, Division of Gynaecological Endoscopy & Minimally Invasive Therapy, Chang Gung Memorial Hospital, Chang Gung University, Linkou, Taiwan; Department of Obstetrics and Gynecology, University of the Philippines Manila, Philippine General Hospital, Manila, PhilippinesDepartment of Obstetrics & Gynaecology, Division of Gynaecological Endoscopy & Minimally Invasive Therapy, Chang Gung Memorial Hospital, Chang Gung University, Linkou, TaiwanDepartment of Obstetrics & Gynaecology, Division of Gynaecological Endoscopy & Minimally Invasive Therapy, Chang Gung Memorial Hospital, Chang Gung University, Linkou, TaiwanObjective: Minimally invasive radical hysterectomy has been shown to be associated with poorer outcome in an influential prospective, randomized trial. However, many centers worldwide performing minimally invasive radical hysterectomy have data and experience that prove otherwise. We aim to review surgical and oncologic outcomes of patients operated by Laparoscopic Radical Hysterectomy in a tertiary hospital, by experienced surgeons and standardization in radicality, for cervical carcinoma Stage 1A1-1B1 from January 2009 to May 2014. Materials & methods: Standardised surgical technique with Parametrium & Paracolpium resection approach was adopted by qualified and experienced Gynecologic/Gyne-Oncologic Endoscopic & Minimally Invasive Surgeons in performing Laparoscopic Radical Hysterectomy for Cervical Cancer stage 1A1-1B1 from January 2009–May 2014, involving 53 patients. Electronic Medical Record system (EMR) Of Chang Gung Memorial Hospital(Tertiary Referral Centre), Department of Obstetrics & Gynecology was accessed for surgical and oncologic outcomes. Results: Fifty-Three patients operated from January 2009 to May 2014 were followed up for an average of 96.7 months with longest follow-up at 127 months. There were no cases of recurrence or death reported. 5 Year – Survival Rate and 5 Year Disease-Free Survival Rate were 100%. Two patients received post-operative pelvic radiation concurrent with chemotherapy using Cisplatin due to greater than 1/3 cervical stromal invasion. Conclusion: It is vital to standardize minimally invasive surgical techniques for early stage cervical cancer, with focus on adequate radicality and resection which may contribute to excellent survival outcomes. Further international multi-center randomized trial (Minimally Invasive Therapy Versus Open Radical Hysterectomy In Cervical Cancer) will provide justification for continued practice of MIS in early stage cervical cancer.http://www.sciencedirect.com/science/article/pii/S1028455921000644Laparoscopic radical hysterectomyCervical cancerMITOR
collection DOAJ
language English
format Article
sources DOAJ
author Chyi-Long Lee
Kuan-Gen Huang
Peng Teng Chua
Marie Christine Valerie R. Mendoza
Pei San Lee
Siew Yen Lai
spellingShingle Chyi-Long Lee
Kuan-Gen Huang
Peng Teng Chua
Marie Christine Valerie R. Mendoza
Pei San Lee
Siew Yen Lai
Standardization and experience may influence the survival of laparoscopic radical hysterectomy for cervical cancer
Taiwanese Journal of Obstetrics & Gynecology
Laparoscopic radical hysterectomy
Cervical cancer
MITOR
author_facet Chyi-Long Lee
Kuan-Gen Huang
Peng Teng Chua
Marie Christine Valerie R. Mendoza
Pei San Lee
Siew Yen Lai
author_sort Chyi-Long Lee
title Standardization and experience may influence the survival of laparoscopic radical hysterectomy for cervical cancer
title_short Standardization and experience may influence the survival of laparoscopic radical hysterectomy for cervical cancer
title_full Standardization and experience may influence the survival of laparoscopic radical hysterectomy for cervical cancer
title_fullStr Standardization and experience may influence the survival of laparoscopic radical hysterectomy for cervical cancer
title_full_unstemmed Standardization and experience may influence the survival of laparoscopic radical hysterectomy for cervical cancer
title_sort standardization and experience may influence the survival of laparoscopic radical hysterectomy for cervical cancer
publisher Elsevier
series Taiwanese Journal of Obstetrics & Gynecology
issn 1028-4559
publishDate 2021-05-01
description Objective: Minimally invasive radical hysterectomy has been shown to be associated with poorer outcome in an influential prospective, randomized trial. However, many centers worldwide performing minimally invasive radical hysterectomy have data and experience that prove otherwise. We aim to review surgical and oncologic outcomes of patients operated by Laparoscopic Radical Hysterectomy in a tertiary hospital, by experienced surgeons and standardization in radicality, for cervical carcinoma Stage 1A1-1B1 from January 2009 to May 2014. Materials & methods: Standardised surgical technique with Parametrium & Paracolpium resection approach was adopted by qualified and experienced Gynecologic/Gyne-Oncologic Endoscopic & Minimally Invasive Surgeons in performing Laparoscopic Radical Hysterectomy for Cervical Cancer stage 1A1-1B1 from January 2009–May 2014, involving 53 patients. Electronic Medical Record system (EMR) Of Chang Gung Memorial Hospital(Tertiary Referral Centre), Department of Obstetrics & Gynecology was accessed for surgical and oncologic outcomes. Results: Fifty-Three patients operated from January 2009 to May 2014 were followed up for an average of 96.7 months with longest follow-up at 127 months. There were no cases of recurrence or death reported. 5 Year – Survival Rate and 5 Year Disease-Free Survival Rate were 100%. Two patients received post-operative pelvic radiation concurrent with chemotherapy using Cisplatin due to greater than 1/3 cervical stromal invasion. Conclusion: It is vital to standardize minimally invasive surgical techniques for early stage cervical cancer, with focus on adequate radicality and resection which may contribute to excellent survival outcomes. Further international multi-center randomized trial (Minimally Invasive Therapy Versus Open Radical Hysterectomy In Cervical Cancer) will provide justification for continued practice of MIS in early stage cervical cancer.
topic Laparoscopic radical hysterectomy
Cervical cancer
MITOR
url http://www.sciencedirect.com/science/article/pii/S1028455921000644
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