Epigenetic regulation of intestinal peptide transporter PEPT1 as a potential strategy for colorectal cancer sensitization

Epigenetic regulation of intestinal peptide transporter PEPT1 as a potential strategy for colorectal cancer sensitization

Abstract Human intestinal peptide transporter PEPT1 is commonly repressed in human colorectal cancer (CRC), yet its relationship with sensitivity to the common CRC treatment ubenimex has not previously been elucidated. In this study, we confirmed PEPT1 suppression in CRC using real-time quantitative...

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Bibliographic Details
Main Authors: Yanhong Wang, Jiaqi Wang, Lingrong Yang, Liqing Qiu, Yuhui Hua, Shixiu Wu, Su Zeng, Lushan Yu, Xiaoli Zheng
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03814-5

Internet

https://doi.org/10.1038/s41419-021-03814-5

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