From lipid secretion to cholesterol crystallization in bile. Relevance in cholesterol gallstone disease

Failure of cholesterol homeostasis in the body can lead to cholesterol gallstone disease, the most common and costly gastrointestinal disease. The primum movens in cholesterol gallstone formation is the hypersecretion of hepatic cholesterol; this condition leads to bile chronically surpersaturated w...

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Bibliographic Details
Main Authors: Piero Portincasa, MD, PhD, Antonio Moschetta, Giuseppe Palasciano
Format: Article
Language:English
Published: Elsevier 2002-07-01
Series:Annals of Hepatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119321702