SPAG5 interacts with CEP55 and exerts oncogenic activities via PI3K/AKT pathway in hepatocellular carcinoma

SPAG5 interacts with CEP55 and exerts oncogenic activities via PI3K/AKT pathway in hepatocellular carcinoma

Abstract Background Deregulation of microtubules and centrosome integrity is response for the initiation and progression of human cancers. Sperm-associated antigen 5 (SPAG5) is essential for the spindle apparatus organization and chromosome segregation, but its role in hepatocellular carcinoma (HCC)...

Full description

Bibliographic Details
Main Authors: Yu-Feng Yang, Mei-Fang Zhang, Qiu-Hong Tian, Jia Fu, Xia Yang, Chris Zhiyi Zhang, Hong Yang
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Molecular Cancer
Subjects:
SPAG5
CEP55
miR-363-3p
PI3K/AKT
Hepatocellular carcinoma
Online Access:http://link.springer.com/article/10.1186/s12943-018-0872-3

Internet

http://link.springer.com/article/10.1186/s12943-018-0872-3

Similar Items